Enterobacterales, Carbapenem-Resistant (all genera)

Reportable by Providers and laboratories
Enterobacteriaceae: Carbapenem-Resistant (CRE)

Infectious agent:  Enterobacterales is an order of gram negative rod facultative anaerobes. 

Common Genera:

  • Escherichia 
  • Enterobacter
  • Klebsiella

Other Common Genera:

  • Citrobacter
  • Morganella
  • Proteus
  • Providencia
  • Salmonella
  • Serratia
  • Shigella

Less Common Genera :

  • Alishewanella
  • Alterococcus
  • Aquamonas
  • Aranicola
  • Arsenophonus
  • Azotivirga
  • Blochmannia
  • Brenneria
  • Buchnera
  • Budvicia
  • Buttiauxella
  • Cedecea
  • Cronobacter
  • Dickeya
  • Edwardsiella
  • Edwardsiella
  • Erwinia
  • Ewingella
  • GrimontellaHafnia
  • Kluyvera
  • Leclercia
  • Leminorella
  • Moellerella
  • Obesumbacterium
  • Pantoea
  • Pectobacterium
  • Phlomobacter
  • Photorhabdus
  • Poodoomaamaana
  • Plesiomonas
  • PragiaRahnella
  • Raoultella
  • Samsonia
  • Sodalis
  • Tatumella   
  • Trabulsiella
  • Wigglesworthia
  • Xenorhabdus
  • Yersinia
  • Yokenella

Description of illness: Enterobacterales cause a wide range of clinical infections and are a major cause of nosocomial infections. CRE are Enterobacterales that are nonsusceptible to carbapenem antibiotics and can cause infections with high rates of morbidity and mortality, particularly among persons with prolonged hospitalization, those who are critically ill, and those exposed to invasive devices (e.g., ventilators or central venous catheters). Symptoms may manifest thru respiratory, wound, urinary tract, invasive, tissue, and other infections.  CRE have become resistant to all or nearly all available antibiotics and therefore are classified by the Centers for Disease Control and Prevention (CDC) as an urgent threat.